Various factors affect how long the opioid painkiller Percocet will stay in your system, including what is being tested, your physiology and the drug’s half-life. Percocet is likely to stay in your system up to 20 hours, but depending on the type of drug test it can still be detected up to 90 days after use.
Percocet is a commonly-prescribed opioid painkiller made from a combination of short-acting oxycodone and acetaminophen. It’s used as a pain-relieving drug to manage acute and chronic pain issues, such as back pain, post-surgical pain or pain due to an accident. However, it is an addictive drug classified as aSchedule II controlled substanceby the Drug Enforcement Administration.
People often wonder how long Percocet lasts in the body and how long it can be detected in routine drug tests. Understanding how long Percocet stays in the system depends on what is being tested, your overall physiology and factors like the drug’s half-life.
What is Percocet’s Half-Life?
Half-life is a term that refers to the amount of time it takes for a substance to reduce to half its initial amount in your body. For example, if you take a substance like Percocet, the half-life refers to how long it takes for the concentration of the substance in your body to decrease by half. Percocet’s half-life may also be helpful to estimate whenwithdrawal symptomsmay occur.
Because the oxycodone component of Percocet is a short-acting, immediate-release drug, its half-life is estimated to bebetween 3.2 and 4 hours. Similarly, the acetaminophen component of Percocet has a half-life ofaround three hours. However, Percocet’s half-life range varies andmay increaseif you have poor kidney or liver function.
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Generally, it takes aboutfive half-livesfor a drug to be completely removed from your system. Based on a half-life of 4 hours, Percocet is likely to stay in your system for about 20 hours.
Factors That Influence How Long Percocet Stays In Your System
There are individual factors that can determine how long Percocet stays in your system:
- Physiological Factors:A person with poor kidney or liver function may clear Percocet slower than a person with healthy kidney and liver function, leading the drug to last longer in their body.
- Drug Interactions:Percocet has some drug interactions that can make the body clear it more quickly than expected,includinganti-infective rifampin and the seizure medications carbamazepine and phenytoin. Some medications can make the painkiller stay in the body longer than expected,includingantibiotics like erythromycin, the antifungal ketoconazole and the HIV medication ritonavir.
- Dosage:The higher the Percocet dose you take and the more often you take it, the longer it may take your body to clear the drug.
How Long Do Percocet’s Effects Last?
When you take Percocet, your gastrointestinal tract initially absorbs it, and peak levels of oxycodone in your blood are reachedwithin two hours. Pain relief starts more quickly, within10 to 15 minutesafter taking Percocet, largely due to the oxycodone component. Peak pain relief is often feltbetween 30 minutes and 1 hourafter taking a dose. The effects are felt for four to six hours, so the medication isusually prescribedto be taken every four to six hours. However, it may show up on a drug test for significantly longer than that.
How Long Will Percocet Show on a Drug Test?
Drug tests do not routinely test for acetaminophen. However, the oxycodone component of Percocet may show up in drug tests for varying amounts of time, depending on what is being tested.
Urine Test
In urine tests, the oxycodone component of Percocet, as well as its breakdown product noroxycodone,can be foundfor up to 3 days. Urine sample tests are common for oxycodone due to their convenience and relatively long testing window.
Blood Test
Percocet can be found in the blood and plasma. The half-life of oxycodone in plasma isbetween 3 and 6 hours, so oxycodone and its metabolite noroxycodone arepresent in blood for between 15 and 30 hours. Blood samples may be used if a person is unconscious or unable to provide a urine sample.
Saliva Test
Opioid-containing drugs like Percocet can befound in saliva forup to 2 days. Some police departments may utilize saliva tests due to the convenience of roadside testing.
Hair Test
A one-inch sample of hair can show oxycodone and its metabolites can bedetected forup to 90 daysafter the last use.
Related Topic:How long do opioids stay in your system
Know the Risks
If you are having concerns about oxycodone showing up on a drug test, it can indicate a struggle with the drug. Oxycodone is ahighly addictive substance. If you need help cutting back or controlling your intake of Percocet, help is available.Contactour addiction experts at The Recovery Village today to learn more abouttreatment optionsthat can help you live a healthier, drug-free life.
